Linebacker London Fletcher and tackle Trent Williams were limited in practice on Friday, Coach Mike Shanahan said.
It was the on-field activity for either player this week.
“We can tell more over the next three days exactly where they are at,” Shanahan said. “You’re keeping your fingers crossed. They both have significant injuries.”
He added: “Chances are [Fletcher] will be ready. But he is quite sore.”
Fletcher has been battling a sprained left ankle that he suffered against the Eagles. Williams, meantime, sustained a deep thigh bruise when he collided with teammate Kory Lichtensteiger in the first quarter against the Cowboys. Williams said earlier this week that he's confident he'll suit up against the Giants.
Fletcher has played in 235 consecutive games, which is tied for the most among active players.
“Hopefully I can feel good enough to play and play well,” Fletcher said. “We still got a few more days until Monday. We don’t know yet. It’s going to come down to a situation of whether I feel like I can go out and be effective or not. I know it’s an important game, but you still have to be able to play well.”